A YOUNG woman has opened up on the “rollercoaster” Mounjaro dose that has left her stomach “crumbling up.”
Simone Wilko, a 19-year-old woman from the UK, has lost six stone thanks to the fat jabs.
However, things haven’t all been smooth sailing for the content creator.
Posting on social media, the self-proclaimed “picky eater” confessed that since increasing her weekly Mounjaro dose to 10mg, she has experienced stomach cramps and dizziness.
Not only this, but Simone, who has been documenting her fat jab journey on her TikTok account, described the increased dose as “absolutely horrible” and claimed that she has been feeling “absolutely awful” since starting it.
As she prepared her dinner, which was her first meal of the day as a result of feeling nauseous, Simone said: “I’ve been on 10mg now for about four weeks and I absolutely hate it – 10mg has been the worst [dose] I’ve been on yet.”
Simone then confirmed: “I normally do my jabs in the evening time and then the next morning and all day, I will be sick, I’ll be having to go to the toilet and it literally makes my stomach crumble up inside and just cramp so much.
“It’s absolutely horrible – it makes me feel dizzy, it makes me not wanna eat.”
Reflecting on her experience with the increased Mounjaro dose, the influencer continued: “It’s absolutely awful and then if I go down to 7.5mg, it won’t work for me – I came off 7.5mg because it didn’t work for me.
“But yeah, it is just a rollercoaster, a constant rollercoaster of being ill.”
Expert reveals all
Following Simone’s claims, Fabulous spoke to the experts to get more information on why this youngster may be experiencing such an adverse reaction to her increased Mounjaro dose.
Dr Ghazala Aziz-Scott, from the Marion Gluck Clinic, told us: “This video highlights the importance of receiving the correct advice and supervision when taking Mounjaro.
“Persistent negative side effects like nausea, vomiting and diarrhoea are a sign of disruption of the body’s normal physiology and will be impacting its health in other ways.”
As a result, the pro recommended: “Before increasing your dose and to avoid further side effects or hitting a plateau, you need to first speak to your provider or healthcare professional about what lifestyle and diet changes can be made first to determine if you do need to increase the dosage or not.”
Everything you need to know about fat jabs
Weight loss jabs are all the rage as studies and patient stories reveal they help people shed flab at almost unbelievable rates, as well as appearing to reduce the risk of serious diseases.
Wegovy – a modified version of type 2 diabetes drug Ozempic – and Mounjaro are the leading weight loss injections used in the UK.
Wegovy, real name semaglutide, has been used on the NHS for years while Mounjaro (tirzepatide) is a newer and more powerful addition to the market.
Mounjaro accounts for most private prescriptions for weight loss and is set to join Wegovy as an NHS staple this year.
How do they work?
The jabs work by suppressing your appetite, making you eat less so your body burns fat for energy instead and you lose weight.
They do this my mimicking a hormone called GLP-1, which signals to the brain when the stomach is full, so the drugs are officially called GLP-1 receptor agonists.
They slow down digestion and increase insulin production, lowering blood sugar, which is why they were first developed to treat type 2 diabetes in which patients’ sugar levels are too high.
Can I get them?
NHS prescriptions of weight loss drugs, mainly Wegovy and an older version called Saxenda (chemical name liraglutide), are controlled through specialist weight loss clinics.
Typically a patient will have to have a body mass index (BMI) of 30 or higher, classifying them as medically obese, and also have a weight-related health condition such as high blood pressure.
GPs generally do not prescribe the drugs for weight loss.
Private prescribers offer the jabs, most commonly Mounjaro, to anyone who is obese (BMI of 30+) or overweight (BMI 25-30) with a weight-related health risk.
Private pharmacies have been rapped for handing them out too easily and video calls or face-to-face appointments are now mandatory to check a patient is being truthful about their size and health.
Are there any risks?
Yes – side effects are common but most are relatively mild.
Around half of people taking the drug experience gut issues, including sickness, bloating, acid reflux, constipation and diarrhoea.
Dr Sarah Jarvis, GP and clinical consultant at patient.info, said: “One of the more uncommon side effects is severe acute pancreatitis, which is extremely painful and happens to one in 500 people.”
Other uncommon side effects include altered taste, kidney problems, allergic reactions, gallbladder problems and hypoglycemia.
Evidence has so far been inconclusive about whether the injections are damaging to patients’ mental health.
Figures obtained by The Sun show that, up to January 2025, 85 patient deaths in the UK were suspected to be linked to the medicines.
Mounjaro users react
Simone’s TikTok clip, which was posted under the username @s33immm, has clearly left many open-mouthed, as it has quickly racked up 362,400 views, 3,927 likes and 529 comments.
But it appears that Simone isn’t the only one to have been experiencing adverse side effects since increasing her dose, as other fat jab users raced to the comments to open up on their similar experiences.
One person said: “This is the same with me. I’ve been sick constantly.”
It’s absolutely horrible – it makes me feel dizzy, it makes me not wanna eat
Simone Wilko
Another added: “10mg was too much for me, I stayed on 7.5mg.”
A third commented: “I agree I’m not doing it anymore. I’m going down to 7.5mg, it’s horrible.”
Meanwhile, someone else chimed in: “The 10mg switch was my worst – I used to get suuuuch terrible heartburn – like to the point of throwing up.”
The dark side of Mounjaro
Not only have many battled unfortunate side effects since using Mounjaro, but last year it was revealed that Scots nurse Susan McGowan, 58, died after taking low-dose injections of the fat jabs over a fortnight.
A probe also found that nearly 400 people have gone to hospital after taking weight loss drugs.
What are the other side effects of weight loss jabs?
Like any medication, weight loss jabs can have side effects.
Common side effects of injections such as Ozempic include:
Nausea: This is the most commonly reported side effect, especially when first starting the medication. It often decreases over time as your body adjusts.
Vomiting: Can occur, often in conjunction with nausea.
Diarrhea: Some people experience gastrointestinal upset.
Constipation: Some individuals may also experience constipation.
Stomach pain or discomfort: Some people may experience abdominal pain or discomfort.
Reduced appetite: This is often a desired effect for people using Ozempic for weight loss.
Indigestion: Can cause a feeling of bloating or discomfort after eating.
Serious side effects can also include:
Pancreatitis: In rare cases, Ozempic may increase the risk of inflammation of the pancreas, known as pancreatitis, which can cause severe stomach pain, nausea, and vomiting.
Kidney problems: There have been reports of kidney issues, including kidney failure, though this is uncommon.
Thyroid tumors: There’s a potential increased risk of thyroid cancer, although this risk is based on animal studies. It is not confirmed in humans, but people with a history of thyroid cancer should avoid Ozempic.
Vision problems: Rapid changes in blood sugar levels may affect vision, and some people have reported blurry vision when taking Ozempic.
Hypoglycemia (low blood sugar): Especially if used with other medications like sulfonylureas or insulin.
While common side effects include nausea, vomiting and diarrhoea, doctors say they have also seen “life-threatening complications”, including seizures, bowel obstruction and inflammation of the pancreas.
The makers of Mounjaro, Lilly UK, said patient safety is its “top priority”.
Lilly UK stressed: “Regulatory agencies conduct extensive independent assessments of the benefits and risks of every new medicine and Lilly is committed to continually monitoring, evaluating, and reporting safety data.
“If anyone is experiencing side effects when taking any Lilly medicine, they should talk to their doctor or other healthcare professional.”
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